[NiFe] Group 2a-hydrogenase

This entry was last updated at: Feb. 9, 2018, 6:36 a.m.

Properties
Group [NiFe] Group 2: Alternative and sensory H2-uptake [NiFe] hydrogenases
Subgroup [NiFe] Group 2a: Cyanobacteria-type
Function Hydrogenotrophic respiration using O2 as the terminal electron acceptor. Important for recycling of H2 produced by nitrogenase and fermentation. Route of electron transfer unresolved.
Activity H2-uptake (unidirectional, some high-affinity)
Oxygen tolerance Some O2-tolerant
Localisation Membrane-associated?
Distribution
Ecosystem distribution Diverse soil and aquatic environments
Taxonomic distribution Widespread among Cyanobacteria and aerobic soil bacteria (e.g. Actinobacteria)
Genetic Organisation

e.g. Mycobacterium smegmatis (WP_003893634.1):

Architecture
Structures
    None
Subunits 3?
Subunit description None
Catalytic site [NiFe]-centre
FeS clusters Proximal: 3Cys1Asn[4Fe4S]
Medial: 3Cys[3Fe4S]
Distal: 3Cys1Glu[4Fe4S]
Sequences in this class
NCBI AccessionOrganismHydrogenase ClassPhylumOrderActivity (Predicted)Oxygen Tolerance (Predicted)Subunits (Predicted)Metal Centres (Predicted)Accessory Subunits (Predicted)
WP_053379275.1Nitrospira moscoviensis[NiFe] Group 2aNitrospiraeNitrospiralesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012681902.1Gemmatimonas aurantiaca[NiFe] Group 2aGemmatimonadetesGemmatimonadalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012536298.1Acidithiobacillus ferrooxidans[NiFe] Group 2aGammaproteobacteriaAcidithiobacillalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_029421095.1Alicyclobacillus macrosporangiidus[NiFe] Group 2aFirmicutesBacillalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_027417151.1Aneurinibacillus terranovensis[NiFe] Group 2aFirmicutesBacillalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_003250668.1Geobacillus thermoglucosidasius[NiFe] Group 2aFirmicutesBacillalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_013076467.1Kyrpidia tusciae[NiFe] Group 2aFirmicutesBacillalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_028986316.1Thermicanus aegyptius[NiFe] Group 2aFirmicutesBacillalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_013987182.1Sulfobacillus acidophilus[NiFe] Group 2aFirmicutesClostridialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_014511332.1Thermus thermophilus[NiFe] Group 2aDeinococcus-ThermusThermalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_007308441.1Crocosphaera watsonii[NiFe] Group 2aCyanobacteriaChroococcalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012361536.1Cyanothece sp. ATCC 51142[NiFe] Group 2aCyanobacteriaChroococcalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_008275259.1Cyanothece sp. CCY0110[NiFe] Group 2aCyanobacteriaChroococcalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012599193.1Cyanothece sp. PCC 7424[NiFe] Group 2aCyanobacteriaChroococcalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_013321766.1Cyanothece sp. PCC 7822[NiFe] Group 2aCyanobacteriaChroococcalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015079360.1Anabaena sp. 90[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_011321261.1Anabaena variabilis[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_026092924.1Calothrix sp. PCC 7103[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_006278427.1Cylindrospermopsis raciborskii[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017656008.1Microchaete sp. PCC 7126[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_006194531.1Nodularia spumigena[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012407177.1Nostoc punctiforme[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015115410.1Nostoc sp. PCC 7107[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_010994852.1Nostoc sp. PCC 7120[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015137522.1Nostoc sp. PCC 7524[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_008235596.1Richelia intracellularis[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015122102.1Rivularia sp. PCC 7116[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017747426.1Scytonema hofmanni[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017747421.1Scytonema hofmanni[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_013192388.1Trichormus azollae[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_023069054.1Lyngbya aestuarii[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_009782476.1Lyngbya sp. PCC 8106[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017716714.1Oscillatoria sp. PCC 10802[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_011612815.1Trichodesmium erythraeum[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_016875640.1Chlorogloeopsis fritschii[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_016860569.1Fischerella muscicola[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_026722320.1Fischerella sp. PCC 9431[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_026731079.1Fischerella sp. PCC 9605[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017315132.1Mastigocladopsis repens[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_027846705.1Mastigocoleus testarum[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012615778.1Chloroflexus aggregans[NiFe] Group 2aChloroflexiChloroflexalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_028460308.1Chloroflexus sp. Y-396-1[NiFe] Group 2aChloroflexiChloroflexalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012122267.1Roseiflexus castenholzii[NiFe] Group 2aChloroflexiChloroflexalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_009185102.1Cecembia lonarensis[NiFe] Group 2aBacteroidetesCytophagalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015029646.1Emticicia oligotrophica[NiFe] Group 2aBacteroidetesCytophagalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_026993787.1Flectobacillus major[NiFe] Group 2aBacteroidetesCytophagalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_028526813.1Runella limosa[NiFe] Group 2aBacteroidetesCytophagalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_013921615.1Runella slithyformis[NiFe] Group 2aBacteroidetesCytophagalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_028664870.1Runella zeae[NiFe] Group 2aBacteroidetesCytophagalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012928387.1Spirosoma linguale[NiFe] Group 2aBacteroidetesCytophagalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins

Literature

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