HydDB provides access to an accurate classifier for hydrogenase sequences and a curated database of hydrogenases by known type. The service is provided by the School of Biological Sciences, Monash University and the Bioinformatics Research Centre, Aarhus University.
Dear HydDB user,
A user recently discovered a bug in the HydDB classifier which caused a high number of sequences to be falsely classified as non-hydrogenases. This may have caused wrong and confusing results for a wide range of users. We sincerely apologize for any inconvenience caused by the bug, which has now been fixed. Users should now experience a much more accurate prediction of hydrogenasity.
We hope that HydDB will remain a valuable tool for our users and greatly appreciate all user feedback.
To use the classifier to predict the type of one or more hydrogenases from sequence, either:
Press the "Submit" button to upload the sequences and begin the classification.
If you provided an e-mail address you will receive an e-mail when your job finishes or fails including a link to the results. You will also be able to download the results as a CSV file.
Only sequences encoding the catalytic subunits of hydrogenases will be classified, i.e. those binding the [NiFe]-centre (NiFe-hydrogenases), [FeFe]-centre (FeFe-hydrogenases), or [Fe]-centre (Fe-hydrogenases). Electron-transfer subunits, accessory proteins, and maturation factors cannot be classified by this service.
A job can at most run for 2 hours and atmost 4000 sequences can be submitted. This should be enough for about 2500 sequences to be classified. Results will be stored for 2 weeks. However, we recommend to download the results as they may be deleted due to the rare event of a power outage or server crash.
|Jobs completed in total||2976|
|Sequences classified in total||1398659|
|Jobs completed in the last 24 hours||18|
|Sequences classified in the last 24 hours||18|