This entry was last updated at: Feb. 9, 2018, 7:32 a.m.
Group | [NiFe] Group 1: Respiratory H2-uptake [NiFe] hydrogenases |
Subgroup | [NiFe] Group 1f: Oxygen-protecting |
Function | Unresolved role. Some enzymes mediate hydrogenotrophic respiration using O2 as a terminal electron acceptor. Enzyme also linked to protection from reactive oxygen species, protection of nitrogenase protection, and recycling of nitrogenase-derived H2. |
Activity | H2-uptake (unidirectional)? |
Oxygen tolerance | O2-tolerant? |
Localisation | Membrane-bound |
Ecosystem distribution | Various soil and aquatic environments |
Taxonomic distribution | Present in both aerobic soil bacteria (e.g. Actinobacteria) and anaerobic marine bacteria (e.g. Deltaproteobacteria) |
e.g. Geobacter sulfurreducens (WP_010940798.1):
Structures |
|
Subunits | 3 |
Subunit description | HyoL (hydrogenase large subunit) HyoS (hydrogenase small subunit) HyoE (cytochrome b subunit) |
Catalytic site | [NiFe]-centre |
FeS clusters | Proximal: 3Cys1Asp[4Fe4S] or 3Cys1Asn[4Fe4S] Medial: 3Cys[3Fe4S] Distal: 3Cys1His[4Fe4S] |
NCBI Accession | Organism | Hydrogenase Class | Phylum | Order | Activity (Predicted) | Oxygen Tolerance (Predicted) | Subunits (Predicted) | Metal Centres (Predicted) | Accessory Subunits (Predicted) |
---|---|---|---|---|---|---|---|---|---|
WP_028845527.1 | Thermodesulfovibrio thiophilus | [NiFe] Group 1f | Nitrospirae | Nitrospirales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_028842875.1 | Thermodesulfovibrio islandicus | [NiFe] Group 1f | Nitrospirae | Nitrospirales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_027713781.1 | Desulfuromonas sp. TF | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_027012481.1 | Corynebacterium freiburgense | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_026840074.1 | Geobacter bremensis | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_026441619.1 | Acidobacterium sp. PMMR2 | [NiFe] Group 1f | Acidobacteria | Acidobacteriales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_025324524.1 | Deferrisoma camini | [NiFe] Group 1f | Deltaproteobacteria | Unclassified | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_025252525.1 | Corynebacterium vitaeruminis | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_022865058.1 | Varibaculum cambriense | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_022851572.1 | Geovibrio sp. L21-Ace-BES | [NiFe] Group 1f | Deferribacteres | Deferribacterales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_022397361.1 | Akkermansia sp. CAG:344 | [NiFe] Group 1f | Verrucomicrobia | Verrucomicrobiales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_020678214.1 | Geopsychrobacter electrodiphilus | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_020489980.1 | Dehalobacter sp. FTH1 | [NiFe] Group 1f | Firmicutes | Clostridiales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_020460947.1 | Frankia sp. EAN1pec | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_018637732.1 | Frankia sp. BMG5.12 | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_018502767.1 | Frankia sp. BCU110501 | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_016458088.1 | Corynebacterium pyruviciproducens | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_016422186.1 | Corynebacterium sp. HFH0082 | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_015898101.1 | Acidobacterium capsulatum | [NiFe] Group 1f | Acidobacteria | Acidobacteriales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_015718812.1 | Geobacter sp. M18 | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_014310124.1 | Corynebacterium diphtheriae | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_013885838.1 | Flexistipes sinusarabici | [NiFe] Group 1f | Deferribacteres | Deferribacterales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_013450229.1 | Calditerrivibrio nitroreducens | [NiFe] Group 1f | Deferribacteres | Deferribacterales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_013011747.1 | Denitrovibrio acetiphilus | [NiFe] Group 1f | Deferribacteres | Deferribacterales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_013006836.1 | Deferribacter desulfuricans | [NiFe] Group 1f | Deferribacteres | Deferribacterales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_012546172.1 | Thermodesulfovibrio yellowstonii | [NiFe] Group 1f | Nitrospirae | Nitrospirales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_012529798.1 | Geobacter bemidjiensis | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_012470110.1 | Geobacter lovleyi | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_012421152.1 | Akkermansia muciniphila | [NiFe] Group 1f | Verrucomicrobia | Verrucomicrobiales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_012121625.1 | Roseiflexus castenholzii | [NiFe] Group 1f | Chloroflexi | Chloroflexales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_011957045.1 | Roseiflexus sp. RS-1 | [NiFe] Group 1f | Chloroflexi | Chloroflexales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_011937483.1 | Geobacter uraniireducens | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_010940798.1 | Geobacter sulfurreducens | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_006562194.1 | Oscillochloris trichoides | [NiFe] Group 1f | Chloroflexi | Chloroflexales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_006544185.1 | Frankia sp. EUN1f | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_006062526.1 | Corynebacterium durum | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_005509950.1 | Corynebacterium amycolatum | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_005388873.1 | Corynebacterium glucuronolyticum | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_004512555.1 | Geobacter metallireducens | [NiFe] Group 1f | Deltaproteobacteria | Desulfuromonadales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_004013385.1 | Mobiluncus mulieris | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
WP_004007712.1 | Mobiluncus curtisii | [NiFe] Group 1f | Actinobacteria | Actinomycetales | Anaerobic Uptake | Unknown | 3 | [NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster | Cytochrome b |
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