Hydrogenase Classifier

NCBI Accession	Organism	Hydrogenase Class	Phylum	Order	Activity (Predicted)	Oxygen Tolerance (Predicted)	Subunits (Predicted)	Metal Centres (Predicted)	Accessory Subunits (Predicted)
WP_022854720.1	Thermodesulfobacterium thermophilum	[FeFe] Group A3	Thermodesulfobacteria	Thermodesulfobacteriales	Bifurcating	Labile	3	[FeFe]-centre, 2 x [4Fe4S] clusters	NADH dehydrogenase, thioredoxin
WP_013907653.1	Thermodesulfatator indicus	[FeFe] Group C2	Thermodesulfobacteria	Thermodesulfobacteriales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with methyl-accepting chemotaxis protein
WP_022854121.1	Thermodesulfatator atlanticus	[NiFe] Group 1c	Thermodesulfobacteria	Thermodesulfobacteriales	Anaerobic Uptake	Sensitive	4	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	[FeS] protein, TM subunit
WP_013906919.1	Thermodesulfatator indicus	[NiFe] Group 1c	Thermodesulfobacteria	Thermodesulfobacteriales	Anaerobic Uptake	Sensitive	4	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	[FeS] protein, TM subunit
WP_013909681.1	Thermodesulfobacterium geofontis	[NiFe] Group 1c	Thermodesulfobacteria	Thermodesulfobacteriales	Anaerobic Uptake	Sensitive	4	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	[FeS] protein, TM subunit
WP_028840815.1	Thermodesulfobacterium hveragerdense	[NiFe] Group 1c	Thermodesulfobacteria	Thermodesulfobacteriales	Anaerobic Uptake	Sensitive	4	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	[FeS] protein, TM subunit
WP_013908379.1	Thermodesulfatator indicus	[NiFe] Group 3c	Firmicutes	Thermodesulfobacteriales	Bifurcating	Sensitive	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Polyferredoxin, [FeS] protein
WP_022853555.1	Thermodesulfatator atlanticus	[NiFe] Group 3c	Thermodesulfobacteria	Thermodesulfobacteriales	Bifurcating	Sensitive	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Polyferredoxin, [FeS] protein
WP_028840908.1	Thermodesulfobacterium hveragerdense	[NiFe] Group 3c	Thermodesulfobacteria	Thermodesulfobacteriales	Bifurcating	Sensitive	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Polyferredoxin, [FeS] protein
WP_028841464.1	Thermodesulfobacterium hveragerdense	[NiFe] Group 4g	Thermodesulfobacteria	Thermodesulfobacteriales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_022856172.1	Thermodesulfobacterium thermophilum	[NiFe] Group 4g	Thermodesulfobacteria	Thermodesulfobacteriales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_013905833.1	Pyrococcus yayanosii	[NiFe] Group 3a	Euryarchaeota	Thermococcales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 3 x [4Fe4S] clusters	F420 reductase
WP_015857693.1	Thermococcus gammatolerans	[NiFe] Group 3a	Euryarchaeota	Thermococcales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 3 x [4Fe4S] clusters	F420 reductase
WP_012572521.1	Thermococcus onnurineus	[NiFe] Group 3a	Euryarchaeota	Thermococcales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 3 x [4Fe4S] clusters	F420 reductase
WP_014012057.1	Thermococcus sp. 4557	[NiFe] Group 3a	Euryarchaeota	Thermococcales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 3 x [4Fe4S] clusters	F420 reductase
WP_014788989.1	Thermococcus sp. CL1	[NiFe] Group 3a	Euryarchaeota	Thermococcales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 3 x [4Fe4S] clusters	F420 reductase
WP_010867988.1	Pyrococcus abyssi	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_010868072.1	Pyrococcus abyssi	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_011012029.1	Pyrococcus furiosus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_011012478.1	Pyrococcus furiosus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_010885378.1	Pyrococcus horikoshii	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_013749130.1	Pyrococcus sp. NA2	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_013749017.1	Pyrococcus sp. NA2	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014734005.1	Pyrococcus sp. ST04	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014734228.1	Pyrococcus sp. ST04	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_013905579.1	Pyrococcus yayanosii	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_013904776.1	Pyrococcus yayanosii	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_013466811.1	Thermococcus barophilus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_013466346.1	Thermococcus barophilus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_011251019.1	Thermococcus kodakarensis	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_020953630.1	Thermococcus litoralis	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_004069412.1	Thermococcus litoralis	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_012571493.1	Thermococcus onnurineus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_012571009.1	Thermococcus onnurineus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_015848571.1	Thermococcus sibiricus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_015849791.1	Thermococcus sibiricus	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014012081.1	Thermococcus sp. 4557	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014012582.1	Thermococcus sp. 4557	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014122569.1	Thermococcus sp. AM4	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014788000.1	Thermococcus sp. CL1	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014788486.1	Thermococcus sp. CL1	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_010479591.1	Thermococcus zilligii	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_010479608.1	Thermococcus zilligii	[NiFe] Group 3b	Euryarchaeota	Thermococcales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_010868591.1	Pyrococcus abyssi	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_013905846.1	Pyrococcus yayanosii	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_013467422.1	Thermococcus barophilus	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_015857865.1	Thermococcus gammatolerans	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_015857684.1	Thermococcus gammatolerans	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_004068373.1	Thermococcus litoralis	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_012571234.1	Thermococcus onnurineus	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.

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