[NiFe] Group 2a-hydrogenase

This entry was last updated at: Feb. 9, 2018, 6:36 a.m.

Properties
Group [NiFe] Group 2: Alternative and sensory H2-uptake [NiFe] hydrogenases
Subgroup [NiFe] Group 2a: Cyanobacteria-type
Function Hydrogenotrophic respiration using O2 as the terminal electron acceptor. Important for recycling of H2 produced by nitrogenase and fermentation. Route of electron transfer unresolved.
Activity H2-uptake (unidirectional, some high-affinity)
Oxygen tolerance Some O2-tolerant
Localisation Membrane-associated?
Distribution
Ecosystem distribution Diverse soil and aquatic environments
Taxonomic distribution Widespread among Cyanobacteria and aerobic soil bacteria (e.g. Actinobacteria)
Genetic Organisation

e.g. Mycobacterium smegmatis (WP_003893634.1):

Architecture
Structures
    None
Subunits 3?
Subunit description None
Catalytic site [NiFe]-centre
FeS clusters Proximal: 3Cys1Asn[4Fe4S]
Medial: 3Cys[3Fe4S]
Distal: 3Cys1Glu[4Fe4S]
Sequences in this class
NCBI AccessionOrganismHydrogenase ClassPhylumOrderActivity (Predicted)Oxygen Tolerance (Predicted)Subunits (Predicted)Metal Centres (Predicted)Accessory Subunits (Predicted)
WP_012407177.1Nostoc punctiforme[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015115410.1Nostoc sp. PCC 7107[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_010994852.1Nostoc sp. PCC 7120[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015137522.1Nostoc sp. PCC 7524[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_008235596.1Richelia intracellularis[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_015122102.1Rivularia sp. PCC 7116[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017747426.1Scytonema hofmanni[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017747421.1Scytonema hofmanni[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_013192388.1Trichormus azollae[NiFe] Group 2aCyanobacteriaNostocalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_023069054.1Lyngbya aestuarii[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_009782476.1Lyngbya sp. PCC 8106[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017716714.1Oscillatoria sp. PCC 10802[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_011612815.1Trichodesmium erythraeum[NiFe] Group 2aCyanobacteriaOscillatorialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_013896580.1Mesorhizobium opportunistum[NiFe] Group 2aAlphaproteobacteriaRhizobialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_026607801.1Methylocapsa acidiphila[NiFe] Group 2aAlphaproteobacteriaRhizobialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_012592713.1 Methylocella silvestris[NiFe] Group 2aAlphaproteobacteriaRhizobialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_020176873.1Methyloferula stellata[NiFe] Group 2aAlphaproteobacteriaRhizobialesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_007015744.1Novosphingobium pentaromativorans[NiFe] Group 2aAlphaproteobacteriaSphingomonadalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_011536525.1Sphingopyxis alaskensis[NiFe] Group 2aAlphaproteobacteriaSphingomonadalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_016875640.1Chlorogloeopsis fritschii[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_016860569.1Fischerella muscicola[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_026722320.1Fischerella sp. PCC 9431[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_026731079.1Fischerella sp. PCC 9605[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_017315132.1Mastigocladopsis repens[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_027846705.1Mastigocoleus testarum[NiFe] Group 2aCyanobacteriaStigonematalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins
WP_014511332.1Thermus thermophilus[NiFe] Group 2aDeinococcus-ThermusThermalesAerobic UptakeTolerant5[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster[FeS] protein, hypothetical proteins

Literature

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