[FeFe] Group B-hydrogenase Putative

This entry was last updated at: Feb. 9, 2018, 6:17 a.m.

Properties
Group [FeFe]-hydrogenases
Subgroup [FeFe] Group B: Colonic-type
Function Unconfirmed role. Indirect evidence suggests the hydrogenase is involved in hydrogenogenic fermentation. It may couple reoxidation of ferredoxinred to the evolution of H2.
Activity H2-evolution?
Oxygen tolerance O2-labile
Localisation Cytosolic
Distribution
Ecosystem distribution Gastrointestinal tracts, anoxic soils and sediments
Taxonomic distribution Widespread in colonic Bacteroides, Clostridia, and Actinobacteria
Genetic Organisation

Organisation 1: Clostridium pasteurianum (WP_023976023.1):


Organisation 2: Clostridium carboxyidovorans (WP_007061531.1):

Architecture
Structures
    None
Subunits 1
Subunit description HydM (catalytic subunit)
Catalytic site [FeFe]-centre
FeS clusters Organisation 1: 2 [4Fe4S] clusters
Organisation 2: 3 [4Fe4S] clusters, 1 [2Fe2S] cluste
Sequences in this class
NCBI AccessionOrganismHydrogenase ClassPhylumOrderActivity (Predicted)Oxygen Tolerance (Predicted)Subunits (Predicted)Metal Centres (Predicted)Accessory Subunits (Predicted)
WP_026939128.1Holophaga foetida[FeFe] Group BAcidobacteriaHolophagalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_003148188.1Atopobium rimae[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_009141594.1Collinsella tanakaei[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_009277946.1Olsenella sp. 809[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_012808500.1Atopobium parvulum[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_013252233.1Olsenella uli[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_013708979.1Coriobacterium glomerans[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_021626398.1Atopobium sp. 810[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_021724994.1Olsenella profusa[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028263961.1Atopobium fossor[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_022078722.1Acetobacter sp. CAG:267[FeFe] Group BAlphaproteobacteriaRhodospirillalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_022187469.1Azospirillum sp. CAG:260[FeFe] Group BAlphaproteobacteriaRhodospirillalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_022195425.1Azospirillum sp. CAG:239[FeFe] Group BAlphaproteobacteriaRhodospirillalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_022418160.1Acidiphilium sp. CAG:727[FeFe] Group BAlphaproteobacteriaRhodospirillalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
XP_008856018.1Entamoeba nuttalli[FeFe] Group BAmoebozoaAmoebidaEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_004307174.1Bacteroides ovatus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_004330064.1Alistipes putredinis[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_005679640.1Bacteroides caccae[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_005836589.1Bacteroides uniformis[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_005929426.1Bacteroides salyersiae[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_005941153.1Bacteroides massiliensis[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007209903.1Bacteroides cellulosilyticus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007560478.1Bacteroides plebeius[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007569731.1Bacteroides coprocola[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007665069.1Bacteroides intestinalis[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007748547.1Bacteroides finegoldii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008025884.1Bacteroides xylanisolvens[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008152383.1Parabacteroides johnsonii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_009126776.1Bacteroides fluxus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_009132353.1Bacteroides oleiciplenus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_010665374.1Marinilabilia salmonicolor[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_011964716.1Bacteroides vulgatus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_013547705.1Bacteroides helcogenes[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_013613424.1Odoribacter splanchnicus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_013760215.1Porphyromonas asaccharolytica[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_014299406.1Bacteroides fragilis[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_016266912.1Bacteroides thetaiotaomicron[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_018338302.1Butyricimonas synergistica[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_018357720.1Porphyromonas levii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_021644837.1Bacteroides pyogenes[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_022278255.1Bacteroides coprophilus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_024988140.1Bacteroides acidifaciens[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_025075971.1Bacteroides faecichinchillae[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_025864379.1Prolixibacter bellariivorans[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_025868115.1Bacteroides nordii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_027202830.1Butyricimonas virosa[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_028726954.1Parabacteroides gordonii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_006929576.1Caldithrix abyssi[FeFe] Group BCaldithrixCaldithrixalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_006009278.1Desulfovibrio piger[FeFe] Group BDeltaproteobacteriaDesulfovibrionalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_009380768.1Bilophila sp. 4_1_30[FeFe] Group BDeltaproteobacteriaDesulfovibrionalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone

Literature

Genetics:

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Physiology: