[FeFe] Group B-hydrogenase Putative

This entry was last updated at: Feb. 9, 2018, 6:17 a.m.

Properties
Group [FeFe]-hydrogenases
Subgroup [FeFe] Group B: Colonic-type
Function Unconfirmed role. Indirect evidence suggests the hydrogenase is involved in hydrogenogenic fermentation. It may couple reoxidation of ferredoxinred to the evolution of H2.
Activity H2-evolution?
Oxygen tolerance O2-labile
Localisation Cytosolic
Distribution
Ecosystem distribution Gastrointestinal tracts, anoxic soils and sediments
Taxonomic distribution Widespread in colonic Bacteroides, Clostridia, and Actinobacteria
Genetic Organisation

Organisation 1: Clostridium pasteurianum (WP_023976023.1):


Organisation 2: Clostridium carboxyidovorans (WP_007061531.1):

Architecture
Structures
    None
Subunits 1
Subunit description HydM (catalytic subunit)
Catalytic site [FeFe]-centre
FeS clusters Organisation 1: 2 [4Fe4S] clusters
Organisation 2: 3 [4Fe4S] clusters, 1 [2Fe2S] cluste
Sequences in this class
NCBI AccessionOrganismHydrogenase ClassPhylumOrderActivity (Predicted)Oxygen Tolerance (Predicted)Subunits (Predicted)Metal Centres (Predicted)Accessory Subunits (Predicted)
WP_027629995.1Ruminiclostridium cellobioparum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027633478.1Clostridium hydrogeniformans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027634587.1Clostridium hydrogeniformans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027637669.1Clostridium cadaveris[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027639106.1Clostridium cadaveris[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_027640431.1Lachnoclostridium clostridioforme[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_027642984.1Lachnoclostridium clostridioforme[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027937376.1Anaeroarcus burkinensis[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_028044437.1Stoquefichus massiliensis[FeFe] Group BFirmicutesErysipelotrichalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028085756.1Dorea longicatena[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028263961.1Atopobium fossor[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028329580.1Brachyspira alvinipulli[FeFe] Group BSpirochaetesSpirochaetalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_028527755.1Ruminococcus gauvreauii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028726954.1Parabacteroides gordonii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_028830146.1Proteocatella sphenisci[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_029451048.1Clostridium algidicarnis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_029452114.1Clostridium algidicarnis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_029502583.1Lachnoclostridium phytofermentans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_032508759.1Peptoclostridium difficile[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_032509674.1Peptoclostridium difficile[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
XP_008856018.1Entamoeba nuttalli[FeFe] Group BAmoebozoaAmoebidaEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_012939228.1Acidaminococcus fermentans[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone

Literature

Genetics:

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Physiology: