[FeFe] Group B-hydrogenase Putative

This entry was last updated at: Feb. 9, 2018, 6:17 a.m.

Properties
Group [FeFe]-hydrogenases
Subgroup [FeFe] Group B: Colonic-type
Function Unconfirmed role. Indirect evidence suggests the hydrogenase is involved in hydrogenogenic fermentation. It may couple reoxidation of ferredoxinred to the evolution of H2.
Activity H2-evolution?
Oxygen tolerance O2-labile
Localisation Cytosolic
Distribution
Ecosystem distribution Gastrointestinal tracts, anoxic soils and sediments
Taxonomic distribution Widespread in colonic Bacteroides, Clostridia, and Actinobacteria
Genetic Organisation

Organisation 1: Clostridium pasteurianum (WP_023976023.1):


Organisation 2: Clostridium carboxyidovorans (WP_007061531.1):

Architecture
Structures
    None
Subunits 1
Subunit description HydM (catalytic subunit)
Catalytic site [FeFe]-centre
FeS clusters Organisation 1: 2 [4Fe4S] clusters
Organisation 2: 3 [4Fe4S] clusters, 1 [2Fe2S] cluste
Sequences in this class
NCBI AccessionOrganismHydrogenase ClassPhylumOrderActivity (Predicted)Oxygen Tolerance (Predicted)Subunits (Predicted)Metal Centres (Predicted)Accessory Subunits (Predicted)
WP_006778913.1Lachnoclostridium hathewayi[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_006789546.1Anaeroglobus geminatus[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_006859957.1Marvinbryantia formatexigens[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_006874781.1Anaerotruncus colihominis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_006874974.1Anaerotruncus colihominis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_006905160.1Shuttleworthia satelles[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_006929576.1Caldithrix abyssi[FeFe] Group BCaldithrixCaldithrixalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_006941133.1Megasphaera micronuciformis[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007046798.1Subdoligranulum variabile[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007049654.1Anaerofustis stercorihominis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007059875.1Clostridium carboxidivorans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007061531.1Clostridium carboxidivorans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007064371.1Clostridium carboxidivorans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007157603.1Oribacterium sinus[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007209903.1Bacteroides cellulosilyticus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007289794.1Thermosinus carboxydivorans[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007290224.1Thermosinus carboxydivorans[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007560478.1Bacteroides plebeius[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007569731.1Bacteroides coprocola[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007665069.1Bacteroides intestinalis[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007748547.1Bacteroides finegoldii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007781007.1Desulfosporosinus youngiae[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007861015.1Lachnoclostridium citroniae[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_007863166.1Lachnoclostridium citroniae[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_007953762.1Pelosinus fermentans[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_008025884.1Bacteroides xylanisolvens[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008152383.1Parabacteroides johnsonii[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008369976.1Coprococcus comes[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008409855.1Desulfotomaculum hydrothermale[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008410184.1Desulfotomaculum hydrothermale[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_008713427.1Synergistes sp. 3_1_syn1[FeFe] Group BSynergistetesSynergistalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008724767.1Brachyspira hampsonii[FeFe] Group BSpirochaetesSpirochaetalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_008753040.1Lachnoanaerobaculum saburreum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_008901930.1Peptoniphilus duerdenii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_009126776.1Bacteroides fluxus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_009132353.1Bacteroides oleiciplenus[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_009141594.1Collinsella tanakaei[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_009145673.1Phascolarctobacterium succinatutens[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_009202817.1Anaerostipes hadrus[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_009277946.1Olsenella sp. 809[FeFe] Group BActinobacteriaCoriobacterialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_009380768.1Bilophila sp. 4_1_30[FeFe] Group BDeltaproteobacteriaDesulfovibrionalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_009624657.1Desulfosporosinus sp. OT[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_010073823.1Clostridium cellulovorans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_010235263.1Clostridium arbusti[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_010249420.1Acetivibrio cellulolyticus[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_010293869.1Clostridium senegalense[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_010297806.1Clostridium senegalense[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_010665374.1Marinilabilia salmonicolor[FeFe] Group BBacteroidetesBacteroidalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_010699218.1Treponema denticola[FeFe] Group BSpirochaetesSpirochaetalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_010966505.1Clostridium acetobutylicum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone

Literature

Genetics:

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Physiology: