[FeFe] Group B-hydrogenase Putative

This entry was last updated at: Feb. 9, 2018, 6:17 a.m.

Properties
Group [FeFe]-hydrogenases
Subgroup [FeFe] Group B: Colonic-type
Function Unconfirmed role. Indirect evidence suggests the hydrogenase is involved in hydrogenogenic fermentation. It may couple reoxidation of ferredoxinred to the evolution of H2.
Activity H2-evolution?
Oxygen tolerance O2-labile
Localisation Cytosolic
Distribution
Ecosystem distribution Gastrointestinal tracts, anoxic soils and sediments
Taxonomic distribution Widespread in colonic Bacteroides, Clostridia, and Actinobacteria
Genetic Organisation

Organisation 1: Clostridium pasteurianum (WP_023976023.1):


Organisation 2: Clostridium carboxyidovorans (WP_007061531.1):

Architecture
Structures
    None
Subunits 1
Subunit description HydM (catalytic subunit)
Catalytic site [FeFe]-centre
FeS clusters Organisation 1: 2 [4Fe4S] clusters
Organisation 2: 3 [4Fe4S] clusters, 1 [2Fe2S] cluste
Sequences in this class
NCBI AccessionOrganismHydrogenase ClassPhylumOrderActivity (Predicted)Oxygen Tolerance (Predicted)Subunits (Predicted)Metal Centres (Predicted)Accessory Subunits (Predicted)
WP_019893070.1Allobaculum stercoricanis[FeFe] Group BFirmicutesErysipelotrichalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_020073353.1Ruminiclostridium sporosphaeroides[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_020073385.1Ruminiclostridium sporosphaeroides[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_021170205.1Sporomusa ovata[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_021800342.1Clostridium intestinale[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_021803667.1Clostridium intestinale[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_021874508.1Clostridium chauvoei[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_022743703.1Clostridium saccharobutylicum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_022746733.1Clostridium saccharobutylicum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_023386490.1Youngiibacter fragilis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_023436998.1Clostridium tetani[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_023920581.1Ruminococcus lactaris[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_023975043.1Clostridium pasteurianum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_023976023.1Clostridium pasteurianum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_024621657.1Peptoclostridium mangenotii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_024622567.1Peptoclostridium mangenotii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_024932223.1Clostridium botulinum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_024933083.1Clostridium botulinum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_025640716.1Clostridium ultunense[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_026881775.1Clostridium akagii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_026886567.1Clostridium beijerinckii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_026887424.1Clostridium beijerinckii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_026891848.1Lachnoclostridium aerotolerans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_026892187.1Lachnoclostridium aerotolerans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_026894367.1Clostridiisalibacter paucivorans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_026894721.1Clostridiisalibacter paucivorans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_027090514.1Erysipelatoclostridium saccharogumia[FeFe] Group BFirmicutesErysipelotrichalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027095964.1Ruminiclostridium viride[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027098445.1Clostridium paraputrificum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027098927.1Clostridium paraputrificum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027207458.1Butyrivibrio fibrisolvens[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027365621.1Desulfotomaculum alcoholivorax[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027625395.1Clostridium lundense[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027626678.1Clostridium lundense[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_027629995.1Ruminiclostridium cellobioparum[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027633478.1Clostridium hydrogeniformans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027634587.1Clostridium hydrogeniformans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027637669.1Clostridium cadaveris[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027639106.1Clostridium cadaveris[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_027640431.1Lachnoclostridium clostridioforme[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_027642984.1Lachnoclostridium clostridioforme[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_027937376.1Anaeroarcus burkinensis[FeFe] Group BFirmicutesSelenomonadalesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_028044437.1Stoquefichus massiliensis[FeFe] Group BFirmicutesErysipelotrichalesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028085756.1Dorea longicatena[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028527755.1Ruminococcus gauvreauii[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_028830146.1Proteocatella sphenisci[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_029451048.1Clostridium algidicarnis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_029452114.1Clostridium algidicarnis[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 2 x [4Fe4S] clustersNone
WP_029502583.1Lachnoclostridium phytofermentans[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone
WP_032508759.1Peptoclostridium difficile[FeFe] Group BFirmicutesClostridialesEvolvingLabile1[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] clusterNone

Literature

Genetics:

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Physiology: