Hydrogenase Classifier

NCBI Accession	Organism	Hydrogenase Class	Phylum	Order	Activity (Predicted)	Oxygen Tolerance (Predicted)	Subunits (Predicted)	Metal Centres (Predicted)	Accessory Subunits (Predicted)
WP_013781007.1	Mahella australiensis	[FeFe] Group C3	Firmicutes	Thermoanaerobacterales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_013810321.1	Desulfotomaculum carboxydivorans	[FeFe] Group C3	Firmicutes	Clostridiales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	None
WP_013841414.1	Desulfotomaculum ruminis	[FeFe] Group C3	Firmicutes	Clostridiales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	None
WP_014186009.1	Desulfosporosinus orientis	[FeFe] Group C3	Firmicutes	Clostridiales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_014296384.1	Marinitoga piezophila	[FeFe] Group C3	Thermotogae	Thermotogales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with methyl-accepting chemotaxis protein
WP_014552161.1	Geobacter sulfurreducens	[FeFe] Group C3	Deltaproteobacteria	Desulfuromonadales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_014559402.1	Ignavibacterium album	[FeFe] Group C3	Ignavibacteriae	Ignavibacteriales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with histidine kinase
WP_015722465.1	Geobacter sp. M18	[FeFe] Group C3	Deltaproteobacteria	Desulfuromonadales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_015839082.1	Geobacter sp. M21	[FeFe] Group C3	Deltaproteobacteria	Desulfuromonadales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_020675965.1	Geopsychrobacter electrodiphilus	[FeFe] Group C3	Deltaproteobacteria	Desulfuromonadales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_026841112.1	Geobacter bremensis	[FeFe] Group C3	Deltaproteobacteria	Desulfuromonadales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_028308065.1	Desulfitibacter alkalitolerans	[FeFe] Group C3	Firmicutes	Clostridiales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_029918197.1	Pelobacter seleniigenes	[FeFe] Group C3	Deltaproteobacteria	Desulfuromonadales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_015839082.1	Geobacter sp. M21	[FeFe] Group C3	Deltaproteobacteria	Desulfuromonadales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with transcriptional activator
WP_012939228.1	Acidaminococcus fermentans	[FeFe] Group B	Firmicutes	Selenomonadales	Evolving	Labile	1	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	None
WP_005026529.1	Bilophila wadsworthia	[FeFe] Group A1	Deltaproteobacteria	Desulfovibrionales	Evolving	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters	None
WP_011388069.1	Rhodospirillum rubrum	[NiFe] Group 4b	Alphaproteobacteria	Rhodospirillales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_028450152.1	Chitinibacter tainanensis	[NiFe] Group 4b	Betaproteobacteria	Neisseriales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_028451288.1	Chitinilyticum aquatile	[NiFe] Group 4b	Betaproteobacteria	Neisseriales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_026263170.1	Chitiniphilus shinanonensis	[NiFe] Group 4b	Betaproteobacteria	Neisseriales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_014767907.1	Desulfurococcus fermentans	[NiFe] Group 4b	Crenarchaeota	Desulfurococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_012608688.1	Desulfurococcus kamchatkensis	[NiFe] Group 4b	Crenarchaeota	Desulfurococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_013561596.1	Desulfurococcus mucosus	[NiFe] Group 4b	Crenarchaeota	Desulfurococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_011839350.1	Staphylothermus marinus	[NiFe] Group 4b	Crenarchaeota	Desulfurococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_014737671.1	Thermogladius cellulolyticus	[NiFe] Group 4b	Crenarchaeota	Desulfurococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_010868591.1	Pyrococcus abyssi	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_013905846.1	Pyrococcus yayanosii	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_013467422.1	Thermococcus barophilus	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_015857865.1	Thermococcus gammatolerans	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_015857684.1	Thermococcus gammatolerans	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_004068373.1	Thermococcus litoralis	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_012571234.1	Thermococcus onnurineus	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_012571983.1	Thermococcus onnurineus	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_012572531.1	Thermococcus onnurineus	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_014012072.1	Thermococcus sp. 4557	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_014122750.1	Thermococcus sp. AM4	[NiFe] Group 4d	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_014123101.1	Thermococcus sp. AM4	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_014122941.1	Thermococcus sp. AM4	[NiFe] Group 4b	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_020505780.1	Lamprocystis purpurea	[NiFe] Group 4b	Gammaproteobacteria	Chromatiales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_028842781.1	Thermodesulfovibrio islandicus	[NiFe] Group 4b	Nitrospirae	Nitrospirales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_028845048.1	Thermodesulfovibrio thiophilus	[NiFe] Group 4b	Nitrospirae	Nitrospirales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_012545774.1	Thermodesulfovibrio yellowstonii	[NiFe] Group 4b	Nitrospirae	Nitrospirales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_011833332.1	Methanocorpusculum labreanum	[NiFe] Group 4d	Euryarchaeota	Methanomicrobiales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_004038443.1	Methanofollis liminatans	[NiFe] Group 4d	Euryarchaeota	Methanomicrobiales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_004077410.1	Methanoplanus limicola	[NiFe] Group 4d	Euryarchaeota	Methanomicrobiales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_013329507.1	Methanoplanus petrolearius	[NiFe] Group 4d	Euryarchaeota	Methanomicrobiales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_011449544.1	Methanospirillum hungatei	[NiFe] Group 4d	Euryarchaeota	Methanomicrobiales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_010867842.1	Pyrococcus abyssi	[NiFe] Group 4d	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_011012581.1	Pyrococcus furiosus	[NiFe] Group 4d	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.
WP_010885519.1	Pyrococcus horikoshii	[NiFe] Group 4d	Euryarchaeota	Thermococcales	Evolving	Sensitive	13	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, two [FeS] proteins, seven MRP antiporter subunits, etc.

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