Hydrogenase Classifier

NCBI Accession	Organism	Hydrogenase Class	Phylum	Order	Activity (Predicted)	Oxygen Tolerance (Predicted)	Subunits (Predicted)	Metal Centres (Predicted)	Accessory Subunits (Predicted)
WP_011024634.1	Caldanaerobacter subterraneus	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_026485852.1	Caldanaerobius polysaccharolyticus	[FeFe] Group A3	Firmicutes	Thermoanaerobacterales	Bifurcating	Labile	4	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin, thioredoxin
WP_026485859.1	Caldanaerobius polysaccharolyticus	[FeFe] Group C1	Firmicutes	Thermoanaerobacterales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_026486855.1	Caldanaerobius polysaccharolyticus	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_017890120.1	Caldatribacterium californiense	[FeFe] Group A1	Atribacteria	Unclassified	Evolving	Labile	1	[FeFe]-centre, 3 x [4Fe4S] clusters, 2 x [2Fe2S] cluster	None
WP_017873317.1	Caldatribacterium californiense	[FeFe] Group C3	Atribacteria	Unclassified	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Phosphatase
WP_017890430.1	Caldatribacterium californiense	[NiFe] Group 3b	Atribacteria	Unclassified	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_026137213.1	Caldatribacterium saccharofermentans	[FeFe] Group A1	Atribacteria	Unclassified	Evolving	Labile	1	[FeFe]-centre, 3 x [4Fe4S] clusters, 2 x [2Fe2S] cluster	None
WP_017890116.1	Caldatribacterium saccharofermentans	[FeFe] Group C3	Atribacteria	Unclassified	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Phosphatase
WP_017873497.1	Caldatribacterium saccharofermentans	[NiFe] Group 3b	Atribacteria	Unclassified	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_020864100.1	Caldiarchaeum subterraneum	[NiFe] Group 3b	Thaumarchaeota	Unclassified	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_029228227.1	Caldicellulosiruptor acetigenus	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_015907776.1	Caldicellulosiruptor bescii	[FeFe] Group A3	Firmicutes	Thermoanaerobacterales	Bifurcating	Labile	4	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin, thioredoxin
WP_015907773.1	Caldicellulosiruptor bescii	[FeFe] Group C1	Firmicutes	Thermoanaerobacterales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_013403316.1	Caldicellulosiruptor hydrothermalis	[FeFe] Group A3	Firmicutes	Thermoanaerobacterales	Bifurcating	Labile	4	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin, thioredoxin
WP_013403323.1	Caldicellulosiruptor hydrothermalis	[FeFe] Group C1	Firmicutes	Thermoanaerobacterales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_013403527.1	Caldicellulosiruptor hydrothermalis	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_013432390.1	Caldicellulosiruptor kristjanssonii	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_013430372.1	Caldicellulosiruptor kronotskyensis	[FeFe] Group A3	Firmicutes	Thermoanaerobacterales	Bifurcating	Labile	4	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin, thioredoxin
WP_013430365.1	Caldicellulosiruptor kronotskyensis	[FeFe] Group C1	Firmicutes	Thermoanaerobacterales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_014042067.1	Caldicellulosiruptor lactoaceticus	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_013290549.1	Caldicellulosiruptor obsidiansis	[FeFe] Group A3	Firmicutes	Thermoanaerobacterales	Bifurcating	Labile	4	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin, thioredoxin
WP_013290556.1	Caldicellulosiruptor obsidiansis	[FeFe] Group C1	Firmicutes	Thermoanaerobacterales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_013290727.1	Caldicellulosiruptor obsidiansis	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_013412032.1	Caldicellulosiruptor owensensis	[FeFe] Group A3	Firmicutes	Thermoanaerobacterales	Bifurcating	Labile	4	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin, thioredoxin
WP_013412025.1	Caldicellulosiruptor owensensis	[FeFe] Group C1	Firmicutes	Thermoanaerobacterales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_013411862.1	Caldicellulosiruptor owensensis	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_013412025.1	Caldicellulosiruptor owensensis	[FeFe] Group C1	Firmicutes	Thermoanaerobacterales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_011917066.1	Caldicellulosiruptor saccharolyticus	[NiFe] Group 4e	Firmicutes	Thermoanaerobacterales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_014433201.1	Caldilinea aerophila	[NiFe] Group 3b	Chloroflexi	Caldilineales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_014434113.1	Caldilinea aerophila	[NiFe] Group 3d	Chloroflexi	Caldilineales	Bidirectional	Tolerant	4	[NiFe]-centre, 1 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_013450229.1	Calditerrivibrio nitroreducens	[NiFe] Group 1f	Deferribacteres	Deferribacterales	Anaerobic Uptake	Unknown	3	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	Cytochrome b
WP_013451671.1	Calditerrivibrio nitroreducens	[NiFe] Group 3d	Deferribacteres	Deferribacterales	Bidirectional	Tolerant	4	[NiFe]-centre, 1 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_006928134.1	Caldithrix abyssi	[FeFe] Group A3	Caldithrix	Caldithrixales	Bifurcating	Labile	3	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin
WP_006929576.1	Caldithrix abyssi	[FeFe] Group B	Caldithrix	Caldithrixales	Evolving	Labile	1	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	None
WP_006928132.1	Caldithrix abyssi	[FeFe] Group C3	Caldithrix	Caldithrixales	Sensory	Labile	1	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Fusion with histidine kinase
WP_006930451.1	Caldithrix abyssi	[NiFe] Group 1d	Caldithrix	Caldithrixales	Aerobic Uptake	Tolerant	3	[NiFe]-centre, 1 x [4Fe3S] cluster, 1 x [3Fe4S] cluster, 1 x [4Fe4S] cluster	Cytochrome b
WP_006926982.1	Caldithrix abyssi	[NiFe] Group 3b	Caldithrix	Caldithrixales	Bidirectional	Tolerant	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Diaphorase, [FeS] protein
WP_006930005.1	Caldithrix abyssi	[NiFe] Group 3c	Caldithrix	Caldithrixales	Bifurcating	Sensitive	4	[NiFe]-centre, 3 x [4Fe4S] clusters	Polyferredoxin, [FeS] protein
WP_008907580.1	Caloramator australicus	[FeFe] Group A3	Firmicutes	Clostridiales	Bifurcating	Labile	4	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin, thioredoxin
WP_008909765.1	Caloramator australicus	[FeFe] Group A3	Firmicutes	Clostridiales	Bifurcating	Labile	3	[FeFe]-centre, 3 x [4Fe4S] clusters, 1 x [2Fe2S] cluster	NADH dehydrogenase, thioredoxin
WP_008909343.1	Caloramator australicus	[FeFe] Group C1	Firmicutes	Clostridiales	Sensory	Labile	2	[FeFe]-centre, 2 x [4Fe4S] clusters, PAS domain	Histidine kinase
WP_008909589.1	Caloramator australicus	[NiFe] Group 1a	Firmicutes	Clostridiales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 3 x [4Fe4S] clusters	Cytochrome
WP_008908605.1	Caloramator australicus	[NiFe] Group 4g	Firmicutes	Clostridiales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_027308223.1	Caloramator sp. ALD01	[NiFe] Group 4g	Firmicutes	Clostridiales	Evolving	Sensitive	6	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, NuoC, [FeS] protein
WP_026092924.1	Calothrix sp. PCC 7103	[NiFe] Group 2a	Cyanobacteria	Nostocales	Aerobic Uptake	Tolerant	5	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	[FeS] protein, hypothetical proteins
WP_007473991.1	Caminibacter mediatlanticus	[NiFe] Group 1b	Epsilonproteobacteria	Nautiliales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	Cytochrome
WP_007474315.1	Caminibacter mediatlanticus	[NiFe] Group 1b	Epsilonproteobacteria	Nautiliales	Anaerobic Uptake	Sensitive	3	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	Cytochrome
WP_007473987.1	Caminibacter mediatlanticus	[NiFe] Group 2d	Epsilonproteobacteria	Nautiliales	Anaerobic Uptake	Unknown	2	[NiFe]-centre, 2 x [4Fe4S] clusters, 1 x [3Fe4S] cluster	None
WP_007473606.1	Caminibacter mediatlanticus	[NiFe] Group 4a	Epsilonproteobacteria	Nautiliales	Evolving	Sensitive	6 or 9	[NiFe]-centre, 1 x [4Fe4S] clusters	NuoL, NuoH, two [FeS] proteins, (three antiporter subunits)

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