[NiFe] Group 2b-hydrogenase

This entry was last updated at: June 13, 2016, 11:11 a.m.

Literature

Genetics:

• Black, L.K., Fu, C., and Maier, R.J. (1994) Sequences and characterization of hupU and hupV genes of Bradyrhizobium japonicum encoding a possible nickel-sensing complex involved in hydrogenase expression. J. Bacteriol. 176: 7102-7106.
• Colbeau, A. and Vignais, P.M. (1992) Use of hupS::lacZ gene fusion to study regulation of hydrogenase expression in Rhodobacter capsulatus: stimulation by H₂. J. Bacteriol. 172: 4258-4264.
• Dischert, W., Vignais, P.M., and Colbeau, A. (1999) The synthesis of Rhodobacter capsulatus HupSL hydrogenase is regulated by the two-component HupT/HupR system. Mol. Microbiol. 34: 995-1006
• Elsen, S., Colbeau, A., Chabert, J., and Vignais, P.M. (1996) The hupTUV operon is involved in negative control of hydrogenase synthesis in Rhodobacter capsulatus. J. Bacteriol. 178: 5174-5181.
• Prosser, J., Graham, L., and Maier, R.J. (1988) Hydrogen-mediated enhancement of hydrogenase expression in Azotobacter vinelandii. J. Bacteriol. 170: 1990-1993.
• Rey, F.E., Oda, Y. and Harwood, C.S. (2006) Regulation of uptake hydrogenase and effects of hydrogen utilization on gene expression in Rhodopseudomonas palustris. J. Bacteriol. 188: 6143-6152.
• Schwartz, E., Buhrke, T., Gerischer, U., and Friedrich, B. (1999) Positive transcriptional feedback controls hydrogenase expression in Alcaligenes eutrophus hydrogenase genes. J. Bacteriol. 181: 5684-5692.
• Schwartz, E., Gerischer, U., and Friedrich, B. (1998) Transcriptional regulation of Alcaligenes eutrophus hydrogenase genes. J. Bacteriol. 180: 3197-3204.
• Vignais, P.M., Billoud, B., and Meyer, J. (2001) Classification and phylogeny of hydrogenases. FEMS Microbiol. Rev. 25: 455-501.
• Lenz, O., Stack, A., Tran-Betcke, A., Friedrich, B. (1997) A hydrogen-sensing system in transcriptional regulation of hydrogenase gene expression in Alcaligenes species. J. Bacteriol. 179: 1655-1663.

Physiology:

• Friedrich, B., Buhrke, T., Burgdorf, T., and Lenz, O. (2005) A hydrogen-sensing multiprotein complex controls aerobic hydrogen metabolism in Ralstonia eutropha. Biochem. Soc. Trans. 33: 97-101.
• Greening, C. and Cook, G. (2014) Integration of hydrogenase expression and hydrogen sensing in bacterial cell physiology. Curr. Opin. Microbiol. 18: 30-38.
• Kleihues, L., Lenz, O., Bernhard, M., Buhrke, T., and Friedrich, B. (2000) The H₂ sensor of Ralstonia eutropha is a member of the subclass of regulatory [NiFe]-hydrogenases. J. Bacteriol. 182: 2716-2724.
• Lenz, O. and Friedrich, B. (1998). A novel multicomponent regulatory system mediates H₂ sensing in Alcaligenes eutrophus. Proc. Acad. Natl. Sci. U.S.A. 95: 12474-12479.

Biochemistry:

• Bernhard, M., Buhrke, T., Bleijlevens, B., de Lacey, A.L., Fernandez, V.M., Albracht, S.P., and Friedrich, B. (2001) The H₂ sensor of Ralstonia eutropha. Biochemical characteristics, spectroscopic properties, and its interaction with a histidine kinase. J. Biol. Chem. 276: 15592-15597.
• Buhrke, T., Lenz, O., Krauss, N., and Friedrich, B. (2005) Oxygen tolerance of the H₂-sensing [NiFe] hydrogenase from Ralstonia eutropha H16 is based on limited access of oxygen to the active site. J. Biol. Chem. 280: 23791-23796.
• Buhrke, T., Lenz, O., Porthun, A., and Friedrich, B. (2004). The H₂-sensing complex of Ralstonia eutropha: interaction between a regulatory [NiFe] hydrogenase and a histidine kinase. Mol. Microbiol. 51: 1677-1689.
• Duché, O, Elsen, S., Cournac, L., and Colbeau, A. (2005) Enlarging the gas access channel to the active site renders the regulatory hydrogenase HupUV of Rhodobacter capsulatus O₂ sensitive without affecting its transductory activity. FEBS J. 272: 3899-3908.
• Elsen, S., Duché, O., and Colbeau, A. (2003) Interaction between the H₂ sensor HupUV and the histidine kinase HupT controls HupSL hydrogenase synthesis in Rhodobacter capsulatus. J. Bacteriol. 185: 7111-7119.
• Gebler, A., Burgdorf, T., de Lacey, A.L., Rüdiger, O., Martinez-Arias, A., Lenz, O., and Friedrich, B. (2007) Impact of alterations near the [NiFe] active site on the function of the H₂ sensor from Ralstonia eutropha. FEBS J. 274: 74-85.

Chemistry

• Ash, P.A., Liu, J., Coutard, N., Heidary, N., Horch, M., Gudim, I., Simler, T., Zebger, I., Lenz, O., and Vincent, K.A. (2015) Electrochemical and infrared spectroscopic studies provide insight into reactions of the NiFe regulatory hydrogenase from Ralstonia eutropha with O₂ and CO. J. Phys. Chem. B. 119: 13807-13815.
• Brecht, M., van Gastel, M., Buhrke, T., Friedrich, B., and Lubitz, W. (2003) Direct detection of a hydrogen ligand in the [NiFe] center of the regulatory H₂-sensing hydrogenase from Ralstonia eutropha in its reduced state by HYSCORE and ENDOR spectroscopy. J. Am. Chem. Soc. 125: 13073-13083.
• Haumann, M., Porthun, A., Buhrke, T., Liebisch, P., Meyer-Klaucke, W., Friedrich, B., and Dau, H. (2003) Hydrogen-induced structural changes at the nickel site of the regulatory [NiFe] hydrogenase from Ralstonia eutropha detected by X-ray absorption spectroscopy. Biochem. 42: 11004-11015.
• Löscher, S., Gebler, A., Stein, M., Sanganas, O., Buhrke, T., Zebger, I., Dau, H., Friedrich, B., Lenz, O., and Haumann, M. (2010) Protein-protein complex formation affects the Ni-Fe and Fe-S centers in the H₂-sensing regulatory hydrogenase from Ralstonia eutropha H16. Chemphyschem 11: 1297-1306.
• Pierik, A.J., Schmelz, M., Lenz, O., Friedrich, B., and Albracht, S.P.J. (1998) Characterization of the active site of a hydrogen sensor from Alcaligenes eutrophus. FEBS J. 428: 231-235.
• Roncaroli, F., Bill, E., Friedrich, B., Lenz, O., Lubitz, W., and Pandelia, M.E. (2015) Cofactor composition and function of a H₂-sensing regulatory hydrogenase as revealed by Mössbauer and EPR spectroscopy. Chem. Sci. 6: 4495-4507.